The phase coherence of light from extragalactic sources - direct evidence against first order Planck scale fluctuations in time and space

We present a method of directly testing whether time continues to have its usual meaning on scales of <= t_P = sqrt(hbar G/c^5) ~ 5.4E-44 s, the Planck time. According to quantum gravity, the time t of an event cannot be determined more accurately than a standard deviation of the form sigma_t/t = a_o (t_P/t)^a, where a_o and a are positive constants ~1; likewise distances are subject to an ultimate uncertainty c \sigma_t, where c is the speed of light. As a consequence, the period and wavelength of light cannot be specified precisely; rather, they are independently subject to the same intrinsic limitations in our knowledge of time and space, so that even the most monochromatic plane wave must in reality be a superposition of waves with varying omega and {\bf k}, each having a different phase velcocity omega/k. For the entire accessible range of the electromagnetic spectrum this effect is extremely small, but can cumulatively lead to a complete loss of phase information if the emitted radiation propagated a sufficiently large distance. Since, at optical frequencies, the phase coherence of light from a distant point source is a necessary condition for the presence of diffraction patterns when the source is viewed through a telescope, such observations offer by far the most sensitive and uncontroversial test. We show that the HST detection of Airy rings from the active galaxy PKS1413+135, located at a distance of 1.2 Gpc, secures the exclusion of all first order (a=1) quantum gravity fluctuations with an amplitude a_o > 0.003. The same result may be used to deduce that the speed of light in vacuo is exact to a few parts in 10^32.Comment: Title change. One reference added. Final version accepted by ApJ

Evaluation of aerosolized medications during parabolic flight maneuvers

The goal was to visually evaluate the effect gravity has on delivery of medications by the use of various aerosol devices. During parabolic flight the same four aerosols were retested as performed in studio ground tests. It appears that the Cetacaine spray and the Ventolin inhaler function without failure during all test. The pump spray (Nostril) appeared to function normally when the container was full, however it appeared to begin to fail to deliver a full mist with larger droplet size when the container was nearly empty. The simple hand spray bottle appeared to work when the container was full and performed progressively worse as the container was emptied. During Apollo flights, it was reported that standard spray bottles did not work well, however, they did not indicate why. It appears that we would also conclude that standard spray bottles do not function as well in zero gravity by failing to produce a normal mist spray. The standard spray bottle allowed the fluid to come out in a narrow fluid stream when held with the nozzle either level or slightly tilted upward

Activation of σ28-dependent transcription inEscherichia coliby the cyclic AMP receptor protein requires an unusual promoter organization

The Escherichia coli aer regulatory region contains a single promoter that is recognized by RNA polymerase containing the flagellar sigma factor, σ28. Expression from this promoter is dependent on direct activation by the cyclic AMP receptor protein, which binds to a target centred 49.5 base pairs upstream from the transcript start. Activator-dependent transcription from the aer promoter was reconstituted in vitro, and a tethered inorganic nuclease was used to find the position of the C-terminal domains of the RNA polymerase α subunits in transcriptionally competent open complexes. We report that the ternary activator-RNA polymerase-aer promoter open complex is organized differently from complexes at previously characterized promoters. Among other E. coli promoters recognized by RNA polymerase containing σ28, only the trg promoter is activated directly by the cyclic AMP receptor protein. The organization of the different promoter elements and the activator binding site at the trg promoter is the same as at the aer promoter, suggesting a common activation mechanism

An Examination of US Consumer Pet and Veterinary Expenditures, 1980-1999

The veterinary medical profession touches nearly everyone's life, either directly or indirectly. An estimated 58.3% of US households own pets (AVMA, 2002), and most people consume livestock products in the form of meat, dairy products, wool, or leather. The health and well being of all these animals depend heavily on relationships with veterinarians. Veterinarians also contribute to public health through the FDA, CDC, USDA, and numerous other government agencies at the federal, state, and local levels. Issues of primary concern include food safety, biosecurity, and the numerous emerging (and re-emerging) infectious diseases that are zoonotic in nature. Finally, veterinarians have an additional impact through their research contributions. Virtually all of the laboratory animals used in research are raised, housed, and managed under the care of veterinarians, and veterinary researchers regularly provide valuable contributions to the knowledge base in the biomedical sciences. This study was designed to assess the general trends in pet and veterinary expenditures as well as factors associated with pet ownership and expenditures on veterinary medical services. Providing such key information on the sector of greatest economic importance will enhance the probability of sustained economic viability in the veterinary medical profession as a whole.Health Economics and Policy,

The Effect of Recombinant Bovine Somatotropin on Patterns of Milk Production, Lactational Milk Estimates and Net Farm Income

Bovine somatoropin (bST) alters total milk production and production patterns in dairy cows and understanding the economic benefits of bST for the dairy producer are critical. Holstein cows (n = 555) from four Michigan dairy farms were randomly assigned as untreated controls or to receive 500 mg of bovine somatotropin (PosilacR) administered every 14 days beginning at 63 to 69 days of lactation and continuing until approximately 21 days prior to the end of lactation or until the animal was removed from the herd. Average peak milk production was 50.8 kg / day and occurred at an average of 113 9 days of lactation for bST-treated cows while average peak production was 48.9 kg / day occurring at an average of 86.4 days of lactation for control cows; both parameters were significantly greater for bST-treated cows compared to controls. Study cows treated with bST were significantly more persistent in lactation (7% greater lactational persistency) compared to control cows. All DHIA estimates and actual milk produced were not significantly different between the study treatment groups for any of the four comparisons made (first, second, third monthly tests after bST treatment initiation and final (305-day) DHIA production estimates); however, the accuracy of DHIA production estimates was significantly affect by the amount of time elapsed since bST but became non-significant by the third DHIA test date. The use of bST changed NFI for each of the four study farms by $96.21,$3.57, $78.71 and ($7.15) per bST-treated cow, respectively during the trial period (from 63 to 305 days of lactation). The overall average change in NFI attributable to bST was $43.01 per bST-treated cow. 2 Profitability of bST use was observed to be quite variable between farms studied because many factors were found to affect the change in NFI per cow resulting from bST use; the level of production response and the price received for milk had the largest effects on the change in NFI associated with bST use; by contrast, price paid for bST itself and feed had only minimal effects on bST-associated profitability. Diseases that may be associated with bST may reduce the profitability of this product and need to be considered as a cost of bST use if present.bovine somatotropin, dairy, net farm income, Farm Management, Livestock Production/Industries, Productivity Analysis, Research and Development/Tech Change/Emerging,

Externally Dispersed Interferometry for Precision Radial Velocimetry

Externally Dispersed Interferometry (EDI) is the series combination of a fixed-delay field-widened Michelson interferometer with a dispersive spectrograph. This combination boosts the spectrograph performance for both Doppler velocimetry and high resolution spectroscopy. The interferometer creates a periodic spectral comb that multiplies against the input spectrum to create moire fringes, which are recorded in combination with the regular spectrum. The moire pattern shifts in phase in response to a Doppler shift. Moire patterns are broader than the underlying spectral features and more easily survive spectrograph blurring and common distortions. Thus, the EDI technique allows lower resolution spectrographs having relaxed optical tolerances (and therefore higher throughput) to return high precision velocity measurements, which otherwise would be imprecise for the spectrograph alone.Comment: 7 Pages, White paper submitted to the AAAC Exoplanet Task Forc

Buyer power in U.K. food retailing: a 'first-pass' test

Habtu Weldegebriel, University of Warwick Abstract The potential existence of buyer power in U.K. food retailing has attracted the scrutiny of the U.K.'s anti-trust authorities, culminating in the second of two comprehensive regulatory inquiries in recent years. Such inquiries are authoritative but correspondingly time-consuming and costly. Moreover, detection of buyer power has been dogged by the paucity of reliable evidence of its existence. In this paper, we present a simple theoretical model of oligopsony which delivers quasi-reduced form retailer-producer pricing equations with which the null of perfect competition can be tested using readily available market data. Using a cointegrated vector autoregression, we find empirical results that show the null of perfect competition can be rejected in seven of the nine food products investigated. Though not conclusive on the existence of buyer power, the proposed test offers a means via which the behaviour of the retail-producer price spread is consistent with it. At the very least, it can corroborate the concerns of the anti-trust authorities as to whether buyer power is potentially one source of concern

The value of psychological flexibility: Examining psychological mechanisms underpinning a cognitive behavioural therapy intervention for burnout

Little is known of the mechanisms by which interventions for burnout work. Employees of a UK government department were randomly assigned to either a worksite group-based CBT intervention called Acceptance and Commitment Therapy (ACT; n=43), which aimed to increase participants' psychological flexibility, or a waiting list control group (n=57). The ACT group received three half-day sessions of training spread over two and a half months. Data were collected at baseline (T1), at the beginning of the second (T2) and third (T3) workshops, and at six months' follow up (T4). Consistent with ACT theory, analyses revealed that, in comparison to the control group, a significant increase in psychological flexibility from T2 to T3 in the ACT group mediated the subsequent T2 to T4 decrease in emotional exhaustion in that group. Consistent with a theory of emotional burnout development, this significant decrease in emotional exhaustion from T2 to T4 in the ACT group appeared to prevent the significant T3 to T4 increase in depersonalization seen in the control group. Strain also decreased from T2 to T3 in the ACT group only, but no mediator of that improvement was identified. Implications for theory and practice in the fields of ACT and emotional burnout are discussed

Towards practical classical processing for the surface code: timing analysis

Topological quantum error correction codes have high thresholds and are well suited to physical implementation. The minimum weight perfect matching algorithm can be used to efficiently handle errors in such codes. We perform a timing analysis of our current implementation of the minimum weight perfect matching algorithm. Our implementation performs the classical processing associated with an nxn lattice of qubits realizing a square surface code storing a single logical qubit of information in a fault-tolerant manner. We empirically demonstrate that our implementation requires only O(n^2) average time per round of error correction for code distances ranging from 4 to 512 and a range of depolarizing error rates. We also describe tests we have performed to verify that it always obtains a true minimum weight perfect matching.Comment: 13 pages, 13 figures, version accepted for publicatio